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Barbiturates are nonselective CNS depressants that used to be the mainstay of treatment to sedate patients or to induce and maintain sleep.
Nondrug therapies include saline or salt-water nasal sprays, exercise, and nasal strips.
If a daily antihistamine is needed during pregnancy, second generation agents are preferred because they are less sedating and have a better side effect profile (have fewer anticholingeric side effects).
Antihistamines are classified into two groups – the first-generation (“sedating”) and second-generation (“non-sedating”).
Sedating antihistamines cause sedation as they are highly lipid soluble and readily cross the blood brain barrier.
Antihistamines work by blocking the effects of a chemical called histamine that is responsible for many allergic symptoms.
Patients who experience significant allergic symptoms regularly may take daily antihistamines to keep their symptoms under control.This sedating activity is sometimes used in managing conditions such as eczema where sleep maybe disturbed due to pruritus.Sedating antihistamines also have significant antimuscarinic activity and should be used with caution in patients with prostatic hypertrophy, urinary retention and angle-closure glaucoma.Antihistamines also can be used on an as needed basis for those who experience occasional symptoms or symptoms triggered by exposure to certain irritants such as animal hair, plants, medications, and food products.Some antihistamines also may be used occasionally to help with sleep.The newer antihistamines (second generation) are less likely to cause these side effects. Long-acting antihistamines provide symptom relief for up to 8-12 hours, while shorter acting agents last for up to 4 hours but begin working faster.Tags: Adult Dating, affair dating, sex dating