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The hardy nose is a remarkable organ designed to condition inhaled air to protect the delicate internal structures.

When breathing through the nose, you may breathe in air at 40 or 100 degrees Fahrenheit, but within a quarter of a second, the air temperature is quickly brought to 98.6.

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Anemia can result in fatigue and other symptoms, including decreased ability to learn.

Paroxysmal cold hemoglobinuria is another specific type of cold allergy, often associated with syphilis, in which cold temperatures make the urine turn red with blood.

Most people don’t know that allergies can be transmitted in transfusions, but they can (Nelson Textbook of Pediatrics, WB Saunders, 2000)!

For some people, cold urticaria is a lifelong condition; for others, it is temporary — only during and after an infection, such as mycoplasma or mononucleosis.

The immune system is an intricate, interconnected network designed to protect our bodies from the dangers of the world around us, especially the danger of invasion from infectious organisms of all types or from the civil war of our own cancerous cells turned against us.

The immune system includes many types of white blood cells, lymph vessels, lymph nodes, a host of specific antibodies, cilia (hair cells for sweeping away unwanted particles), the spleen, tonsils, adenoids, and our largest organ — the flexible, complex barrier we call skin.

Sometimes cold urticaria is a symptom of another problem, such as cryofibrinogenemia, cryoglobulinemia, or syphilis.

Even when it is not, you can develop cold urticaria after receiving a blood transfusion from someone who has it.

Treatment of cold urticaria involves avoiding the cold, when possible, and taking antihistamines.

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